SUDOSCAN
Sudomotor Function Assessment
SUDOSCAN is a new method for sudomotor function assessment. It measures sweat composition to
detect deviations in the ionic balance of sweat.
SUDOSCAN is used by medical practitioners to analyze sweat gland dysfunction associated with
small nerve fiber neuropathy, not necessarily detectable in physiological conditions. It is
non-invasive, painless, and takes only 2 minutes.
Quantitative results are expressed as Electrochemical Sweat Conductance (ESC, in microsiemens,
µS) for the hands and feet. A relative risk score demonstrating the severity of dysautonomia
is derived from ESC values and demographic data.
SUDOSCAN produces detailed reports and quantitative data, which further enhance the medical
professional's ability to pinpoint the etiology of disease resulting from disturbances in the
Autonomic Nervous System (ANS). Keep in mind that about 33% of small fiber neuropathies remain
idiopathic despite appropriate diagnostic evaluation.
Early detection of Small Fiber Neuropathy allows for continual management of a progressive
disease. Routine quantifiable assessment necessitates an individualized patient-centric
approach to the underlying causes of neuropathy.
SUDOSCAN has been tested for small fiber nerve neuropathies in several diseases and compared to
guidelines reference tests:
- Diabetes
- Parkinson
- Chemotherapy induced polyneuropathy
- Familial amyloid polyneuropathy
- Fabry disease
Cardiovascular Autonomic Neuropathy (CAN) is clinically the most critical form of diabetic
autonomic neuropathy. It is caused by a loss of autonomous cardiac innervation and results in
diminished Heart Rate Variability (HRV) and vascular dynamics. Detecting CAN early can help prevent
sudden cardiac death and myocardial infarction. HRV has proven to be a predictor for all-cause
mortality but is time consuming and requires specific diagnostic equipment.
SUDOSCAN is an innovative device to detect and follow-up cardiac autonomic neuropathy.
